Protocatechuic acid exists in many vegetables and fruits in nature, and is an effective active ingredient in many traditional Chinese medicines (such as Salvia miltiorrhiza, Hibiscus, etc.). Protocatechuic acid is a water-soluble phenolic acid component and active substance of many traditional Chinese medicines. It not only has pharmacological activities such as anti-platelet agglutination, reducing myocardial oxygen consumption, improving myocardial oxygen tolerance, slowing heart rate, bacteriostasis, analgesia, but also has antioxidant, anti-tumor and neuroprotective effects.
The extraction of protocatechuic acid from plants is difficult to form large-scale production because of its low extractable plant sources and low content. Chemical synthesis of protocatechuic acid has been a mature process and large-scale production for many years, but the purity of the product is not high, trace impurities and isomers are uncontrollable, and there are safety risks when it is used as medicine, food and feed. Procatechuic acid produced by bio-enzymatic method has high purity, total content of 99.7%, little other micro-impurities, clear harmless, white color and good dispersion. It is safe to use in medicine.
Nanjing Shunxiang produces protocatechuic acid by biological method (enzymatic method). This method is green, environmentally friendly and sustainable. Compared with chemical method, it has economic competitiveness and has good industrial application prospects.
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